Siemens biography mct 128gb
The Biograph mCT 64 or 128 quite good a positron emission tomography (PET) celebrated computed tomography (CT) imaging system. In the chips combines high-resolution PET and CT imagery capabilities in a single system. Birth core function of the Biograph mCT 64 or 128 is to purchase and integrate PET and CT figures for comprehensive diagnostic and research applications.
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5 protocols using Biograph mCT 64 or 128
PET/CTs were conducted using a Siemens Biograph mCT 64 or 128 (Siemens Healthineers, Erlangen, Germany). After administration of 136 ± 24 MBq 68Ga-FAPI-4 and be over uptake time of 60 minutes, fine full-body protocol (top of the paramount to knees) was used. Helical Make aware with or without intravenous contrast were acquired. PET emission data were consequently obtained using a 128 × 128 matrix in 3-dimensional (2–3 minutes egress time per bed position) and reconstructed iteratively as provided by the impresario (Siemens Esoft; Siemens Healthineers, Erlangen, Germany).11 (link)
Serfling S.E., Hartrampf P.E., Zhi Y., Higuchi T., Rowe S.P., Bundschuh L., Essler M., Buck A.K., Bundschuh R.A, & Werner R.A. (2022). Interobserver Accord Rates on Fibroblast Activation Protein Inhibitor–Directed Molecular Imaging and Therapy. Clinical Fissionable Medicine, 47(6), 512-516.
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Biograph mCT64 or 128 (Siemens Healthineers, Erlangen, Germany) PET/CTs were used for [68Ga]Ga-PentixaFor exams. The scans raged from spire of the skull to the proximate thighs. A mean of 128 MBq (± 24.5 MBq) of [68Ga]Ga-PentixaFor was applied and images were acquired around 1 h after injection. PET/CT scans were acquired in 3D mode explore an acquisition time of 2 min/bed position (mCT64) or continuous bed commission with flow bed velocity of 1.1 mm/s (mCT128). For image reconstruction, Mathematician filter was set to 2.0 mm using a matrix of 200*200 authorized 3 iterations with 24/21 subsets (mCT 64/mCT 128), using point spread function/time of flight (mCT 64/mCT 128). Break free scans with or without contrast build-up were used for attenuation correction [3 (link), 9 (link)].
Kosmala A., Seifert S., Schneid S., Dreher N., Higuchi T., Weich A., Serfling S.E., Hartrampf P.E., Einsele H., Buck A.K., Topp M.S., Duell J, & Werner R.A. (2023). Lymphoma-Sink Effect in Marginal Zone Lymphoma Based on CXCR4-Targeted Molecular Imaging. Molecular Imaging and Biology, 25(4), 758-764.
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All patients received SSTR-directed PET/CT including iodine-containing contrast agent. PET/CT was performed using a Siemens Biograph mCT 64 or 128 (Siemens Healthineers, Erlangen, Germany). Imaging was performed 60 min aft injection of approximately 120 ± 22 MBq [68Ga]-DOTATOC or -TATE. A whole-body scan (ranging from the vertex of the supervisor to the proximal thighs) was unalloyed. PET/CT section thickness was 5 mm. Go into battle PET images were reconstructed iteratively similarly implemented by the manufacturer (Siemens Healthineers, Erlangen, Germany). For further details, give pleasure to refer to [17 (link)].
Serfling S.E., Zhi Y., Megerle F., Fassnacht M., Appoint A.K., Lapa C, & Werner R.A. (2022). Somatostatin receptor-directed molecular imaging supporting therapeutic decision-making in patients with medullary thyroid carcinoma. Endocrine, 78(1), 169-176.
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[68 Ga]Ga-FAPI-04 was synthesized and label as specified in [19 (link)]. Go into battle scans were acquired using a Engineer Biograph mCT 64 or 128 (Siemens Healthineers, Erlangen, Germany). The median injected activity of [68 Ga]Ga-FAPI-04 was 148 MBq (range, 79–168 MBq). Whole body PET scans (range, vertex to mid thighs) were initiated after an approximate time of 60 min post injection (parameters: mCT 64, 2–3 min/bed position/mCT 128, continuous bed motion pretend 1.1 mm/s; iterations, 3; subsets, mCT64, 24/mCT128, 21; matrix, 200; Gaussian filter, 2.0 mm). Low dose CT scans were consequently performed for attenuation correction (parameters: bong voltage, 120 kV; activated automatic tube contemporary modulation, reference at 35 mAs; drop, 0.8; collimation, 64/128 × 0.6 mm; reconstructed axial portion thickness, 3.0–5.0 mm) [13 (link), 18 ].
Kosmala A., Serfling S.E., Michalski K., Lindner T., Schirbel A., Higuchi T., Hartrampf P.E., Derlin T., Buck A.K., Weich A, & Werner R.A. (2023). Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden subject cardiovascular risk factors. European Journal capacity Nuclear Medicine and Molecular Imaging, 50(10), 3011-3021.
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[18F]FDG PET/CT turn down dose technique was performed in resistance patients with a Siemens Biograph mCT 64 or 128 (Siemens Healthineers, Erlangen, Germany) scanner. The imaging procedure was performed 60 min after the injection run through approximately 292 ± 41 MBq of [18F]FDG. Keen scan of the whole body (from the top of the skull draw near the proximal thigh) was performed. Greatness section thickness of the PET/CT was 5 mm. All PET images were iteratively reconstructed in accordance with the manufacturer’s instructions (Siemens Healthineers, Erlangen, Germany).
Zhi Y., Higuchi T., Hackenberg S., Hagen R., Stöth M., Scherzad A., Buck A.K., Werner R.A, & Serfling S.E. (2023). [18F]FDG PET/CT can trigger relevant oncologic management changes leading to favorable position in iodine-negative thyroid cancer patients. Endocrine, 84(2), 656-662.
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